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Chao Yan |
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$99.75 |
June 2013 |
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Illustrated: |
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Preface
In recent years, microscale
separation technology has attracted extensive research interest and has proved
to be a powerful analytical tool for a variety of fields. It has the advantages
of high separation efficiency, high resolution, and high selectivity with fast
speed. Solvent and sample consumption is usually 10,000 times lower than with
HPLC, making it economically attractive and environmentally friendly. Since
2006, I have taught a graduate course on contemporary pharmaceutical analysis
at Shanghai Jiao Tong University, and capillary electrokinetic separation
methods are major topics in the course. I have long thought about a book
dedicated to most of the capillary-based liquid separation technologies.
Although microscale separation techniques have been intensively and extensively
reported in the literature and at dedicated conferences, there have been only a
few books dedicated to the broader scope of microscale separation and analysis.
For the purposes of application development and popularization, this book
presents, reviews, and summarizes systematically the advances in contemporary
microscale chromatographic and electrokinetic separation techniques, including
capillary electrophoresis (CE), capillary electrochromtography (CEC),
pressurized CEC (pCEC), micellar electrokinetic chromatography (MEKC),
capillary isoelectric focusing (CIEF), capillary gel electrophoresis (CGE),
capillary isotachophoresis (CITP), and capillary liquid chromatography (CLC),
as well as microchip-based LC and multidimensional capillary separations. The
book covers the fundamentals, instrumentation, and applications of these
techniques to facilitate a systematic understanding for readers.
In spite of the many advances in microseparation techniques, there remain many
technical difficulties and associated problems that need to be further studied
and solved. Still, microscale analysis offers exciting opportunities for
elucidating the mysteries of the separation world. I believe this book will be
helpful to professional chemists and graduate students who either face
challenging problems in developing new methods or need to improve existing
analytical methods with complex samples in the pharmaceutical, biological,
environmental, and chemical fields.
I would like to acknowledge many people for their support and assistance,
especially Dr. Junhua Wang and Prof. Lingjun Li at the University of
Wisconsin--Madison for their contributions to Chapter 4. I also thank my
assistants, Dr. Yan Wang and Dr. Xue Gu, for their industrious efforts. I express
my thanks to my postdoctoral fellow, Dr. Qishu Qu, and many graduate
students, including Juan Wei, Yunyun Xue, Qi Wu, Yuhong Wang, Xiaohui Zhang,
Huiping Zhang, Maer Jiang, and Chaoran Wang for their diligent work in helping
to write this book. I would also like to thank Henry Boehm for his professional
guidance and efforts in the whole process of writing, editing, and publishing
this book.